- HOME
- Products and Service Information
- Fluorinated compounds <General Name > Custom synthesis
Fluorinated compounds <General Name > Custom synthesis
Service overview
AGC Chemicals is a fluorine chemical manufacturer with extensive experience in fluorine chemistry and is equipped with world leading technological and production capabilities able to handle the 4 main halogens.
We have a prolific track record in various types of organic synthesis, general fluorination, halogenation, ultra low temperature reactions, etc.
Using fluorination technology that is our speciality, we offer contract manufacturing of fluorinated compounds matched to our customers' needs from laboratory scale to industrial scale based on efficient process development.
AGC Chemicals contract manufacturing
Owned technology
■ Halogenation
Halogen exchange reactions
Nucleophilic fluorination
Electrophilic fluorination
Diazo fluorination
“PERFECT” process
Electrolysis fluorination
Apart from the above, reactions using anhydrous fluoride (HF), fluorine gas (F2),tetrafluoroethylene (TFE), chlorotrifluoroethylene, (CTFE) and iodine pentafluoride (IF5), etc., are also possible.
■ Ultra low temperature reactions
Down to a minimum temperature of -100°C
■ Use of fluorine-containing building blocks
Heterocyclic compounds
Fluoroalkyl group introduction
■ Various types of organic synthesis
Friedel-Crafts
Grignard
Various types of cross coupling
Oxidation
Reduction (hydrogenation)
High pressure reactions (toxic / combustible high pressure gas)
High temperature reactions
- Photoreactions (e.g.: using UV, etc.)
- Polypetides / oligomerization
- Polymer reactions
- Optically active compounds (enantioselective synthesis)
- Terminal functional group protection
- Distillation (atmospheric distillation, pressurized distillation, vacuum distillation, extraction distillation, water steam distillation)
- Granulation
- Pulverization
- High purity refining
- Use of ion-exchange resins / ion-exchange membranes
- High vacuum
- Use of membrane technology
- Gas phase thermal decomposition reaction
Halogenation (fluorination, chlorination, bromination, iodination)
AGC Chemicals is able to handle the 4 main halogens based on our own company's fluorination technology.
Ultra low temperature reactions
AGC Chemicals has equipment capable of handling temperatures down to -100°C for ultra low temperature reactions that control side reactions.
AGC Inc. Chiba Plant:GL 3000L, HC 1000L
AGC Seimi Chemical Co., Ltd.: 500L x 2, 200L x 1
3. Use of fluorine-containing building blocks
AGC Chemicals also handles the use of and supply fluorine-containing building blocks (molecules with fluorine atoms and terminal functional groups) using our company's tetrafluoroethylene (TFE), chlorotrifluoroethylene, (CTFE) and trifluoroacetic acid, too.
Examples of raw materials that can be used
No. | CAS No. | CHEMICAL NAME |
---|---|---|
1 | 76-05-1 | Trifluoroacetic acid |
2 | 407-25-0 | Trifluoroacetic anhydride |
3 | 383-63-1 | Ethyl trifluoroacetate |
4 | 2923-18-4 | Sodium trifluoroacetate |
5 | 354-38-1 | Trifluoroacetamide |
6 | 677-69-0 | Heptafluoro-2-iodopropane |
7 | 455-14-1 | 4-(trifluoromethyl)aniline |
8 | 122665-97-8 | 4,4-difluorocyclohexane carboxylic acid |
9 | 148043-73-6 | 4,4,5,5,5-Pentafluoro-1-pentanol |
10 | 30071-93-3 | 3,5-Bis(trifluoromethyl)acetophenone |
11 | 3862-73-5 | 2,3,4-Trifluoroaniline |
12 | 328-93-8 | 2,5-Bis(trifluoromethyl)aniline |
13 | 214557-89-8 | 3,5,7-trifluoroadamantane carboxylic acid |
14 | 118612-00-3 | N,N-Dimethylanilinium tetrakis-(pentafluorophenyl)borate |
15 | 136040-19-2 | Triphenylcarbenium tetrakis-(pentafluorophenyl) borate |
16 | 75-29-6 | 2-chloropropane |
17 | 557-98-2 | 2-chloropropene |
18 | 542-75-6 | 1,3-dichloropropene |
19 | 96-18-4 | 1,2,3-trichloropropane |
20 | 142-28-9 | 1,3-dichloropropane |
21 | 96-24-2 | 3-chloro-1,2-propanediol |
22 | 96-23-1 | 1,3-dichloro-2-propanol |
23 | 627-30-5 | 3-chloro-1-propanol |
24 | 616-30-8 | 3-amino-1,2-propanediol |
25 | 107-11-9 | 3-amino-1-propene |
26 | 124-02-7 | diallylamine |
27 | 102-70-5 | triallylamine |
28 | 870787-05-6 | methyl 3-(trifluoromethyl)pyrazine-2-carboxylate |
29 | 873056-62-3 | 3',4'-difluorobiphenyl-2-amine |
Download
PRODUCT LIST